Protein Transport

Process

• DNA is transcribed to form mRNA
• The mRNA leaves the nucleus and moves onto one of the ribosomes on the rough endoplasmic reticulum (rER)
• The proteins are made at the ribosomes on the rER using the mRNA
• These new proteins are folded and processed as they move through the rER, assuming 3D shape en route
• Vesicles xontaining the protein are pinched off the rER
• These vesicles fuse to form the flattened sacs of the Golgi apparatus
• The proteins are modified within the Golgi apparatus
• Vesicles are pinched off the Gogli apparatus that contain the modified protein
• The vesicles fuse with the cell surface membrane releasing the protein

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